Philip Mudd Lab
My primary clinical research focus is improving diagnosis and treatment strategies for patients who present to the emergency department with viral respiratory infections. Recent projects include developing risk stratification tools for patients diagnosed with influenza, understanding the clinical impact of influenza on complications of diabetes and evaluating the utility of diagnostic testing, other than influenza testing, in the workup and management of influenza patients in the ED. In the laboratory, our group studies immune responses directed against influenza virus during acute infection. Our primary focus is the T cell response. We have recruited a cohort of subjects with influenza infection of varying severity diagnosed in the emergency department. We are trying to understand the role that variation in the early immune response and the role that early viral sequence variation play in clinical outcome in these individuals.