Fuller-Publications

Recent Publications

Peer Reviewed Publications

  1. Trzeciak S, Jones AE, Kilgannon JH, Fuller, BM, Roberts BW, Parrillo JE, Farrar JT. Outcome measures utilized in clinical trials of interventions for post-cardiac arrest syndrome: a systematic review. 2009; 80(6): 617-23.
  2. Fuller BM, Dellinger, RP, Hemodynamic resuscitation in septic shock: cardiovascular support and adjunctive therapy. Curr Infect Dis Rep. 2009; 11(5): 357-364.
  3. Fuller BM, Gajera M, Schorr C, Gerber D, Dellinger RP, Parrillo J, Zanotti S. The impact of packed red blood cell transfusion on clinical outcomes in patients with septic shock treated with early goal directed therapy. Indian J Crit Care Med. 2010; 14 (4): 165-169.
  4. Mohr NM, Hotchkiss RS, Micek ST, Durrani S, Fuller BM. Change in temperature profile may precede fever and be an early indicator of sepsis: A case report. Shock; 2011; 36(3): 318-20.
    1. Accompanied by Editorial.
  5. Fuller BM, Gajera M, Schorr C, Gerber D, Dellinger RP, Zanotti, S. The association of prior statin use in septic shock treated with early goal directed therapy. Eur J Emerg Med. 2012; 19 (4): 226-30.
  6. Mohr NM, Fuller BM, Skrupky LP, Moy H, Alunday R, Micek ST, Fagley RE. Clinical and demographic factors associated with antipyretic use in gram-negative severe sepsis and septic shock. Ann Pharmacother. 2011; 45 (10): 1207-16.
  7. Fuller BM, Gajera M, Schorr C, Gerber D, Dellinger RP, Parrillo J, Zanotti S. Transfusion of packed red blood cells is not associated with improved central venous oxygen saturation or organ function in patients with septic shock. J Emerg Med; 2012; 43(4): 593-598.
  8. Fuller BM, Dellinger RP. Lactate as a hemodynamic marker in the critically ill. Curr Opin Crit Care. 2012; 18(3):267-72.
  9. Mohr NM, Fuller BM. Low tidal volume ventilation should be the routine ventilation strategy of choice for all emergency department patients. Ann Emerg Med. 2012 Aug; 60(2):215-6.
  10. Mohr NM, Skrupky LP, Fuller BM, Moy H, Alunday R, Wallendorf MJ, Micek ST, Fagley RE. Early antipyretic exposure does not increase mortality in patients with gram negative severe sepsis: a retrospective cohort study. Intern Emerg Med (2012) 7:463-470.
  11. Fuller BM, Mohr NM, Mueller K, Skrupky L, McCammon C, Emergency department vancomycin use: dosing practices and associated outcomes. J Emerg Med. 2013; 44(5): 910-8.
  12. Fuller BM, Mohr NM, Drewry AM, Carpenter CR. Lower tidal volume at initiation of mechanical ventilation may reduce progression to acute respiratory distress syndrome: a systematic review. Crit Care. 2013; 17(1):R11.
    1. Accompanied by Editorial.
  13. Fuller BM, Mohr NM, Dettmer M, et al. Mechanical ventilation and acute lung injury in emergency department patients with severe sepsis and septic shock: an observational study. Acad Emerg Med. 2013; 20(7): 659-69.
  14. Drewry AM, Fuller BM, Bailey TC, Hotchkiss RS. Body temperature patterns as a predictor of hospital-acquired sepsis in afebrile adult intensive care unit patients: a case-control study. Crit Care. 2013 Sep 12; 17 (5):R200.
  15. Fuller BM, Mohr NM, Hotchkiss RS, Kollef MH. Reducing the burden of acute respiratory distress syndrome: the case for early intervention and the potential role of the emergency department. Shock. 2014 41 (5): 378-387.
  16. Micek ST, Lang A, Fuller BM, Hampton NB, Kollef MH. Clinical implications for patients inappropriately treated for community-acquired pneumonia in the emergency department. BMC Infect Dis. 2014 Feb 5; 14: 61.
  17. Drewry AM, Samra N, Skrupky L, Fuller BM, Compton SM, Hotchkiss RS. Persistent lymphopenia after diagnosis of sepsis predicts mortality. Shock. 2014 Nov; 42(5): 383-91.
  18. Fuller BM, Mohr NM. Limiting acute respiratory distress syndrome in the emergency department: a survey of U.S. academic emergency physicians. Eur J Emerg Med 2014 Oct; 21 (5): 387-8.
  19. Fuller BM, Mohr NM, Graetz TJ, Lynch IP, Dettmer M, Cullison K, Coney T, Gogineni S, Gregory R. The impact of cardiac dysfunction on acute respiratory distress syndrome and mortality in mechanically ventilated patients with severe sepsis and septic shock: An observational study. J Crit Care 2015 Feb; 30(1):65-70.
  20. Dettmer M, Holthaus CV, Fuller BM. The impact of serial lactate monitoring on emergency department resuscitation interventions and clinical outcomes in severe sepsis and septic shock: an observational cohort study. Shock 2015 Jan;43(1):55-61.
  21. Drewry AM, Fuller BM, Skrupky LP, Hotchkiss RS. The presence of hypothermia within 24 hours of sepsis diagnosis predicts persistent lymphopenia. Crit Care Med 2015 Jun;43(6):1165-9.
  22. Mueller K, Skrupky L, McCammon C, Fuller BM. Vancomycin use in patients discharged from the emergency department: a retrospective observational cohort study. J Emerg Med 2015 Jul;49(1):50-7.
  23. Fuller BM, Mohr NM, Skrupky L, Fowler S, Kollef MH, Carpenter C. The use of inhaled prostaglandins in patients with acute respiratory distress syndrome: a systematic review and meta-analysis. Chest 2015 Jun;147(6):1510-22.
  24. Fuller BM, Mohr NM, Miller CN, Deitchman AR, Levine BJ, Castagno N, Hassebroek EC, Dhedhi A, Scott-Wittenborn N, Grace E, Lehew C, Kollef MH. Mechanical ventilation and acute respiratory distress syndrome in the emergency department: a multi-center, observational, prospective, cross-sectional study. Chest 2015 Aug 1;148(2):365-74.
  25. Stoltze AJ, Wong TS, Harland KK, Ahmed A, Fuller BM, Mohr NM. Prehospital tidal volume influences hospital tidal volume: A cohort study. J Crit Care 2015 Jun;30(3):495-501.
  26. Faine BA, Mohr NM, Harland K, Rolfes KA, Porter BA, Fuller BM. Importance of decision support implementation in emergency department vancomycin dosing. West J Emerg Med 2015 Jul;16(4):557-64.
  27. Dettmer M, Mohr NM, Fuller BM. Sepsis-associated pulmonary complications in emergency department patients monitored with serial lactate: an observational cohort study. J Crit Care 2015 Dec; 30(6): 1163-1168.
  28. Faine B, Noack J, Wong TS, Fuller BM, Mohr NM. Inter-hospital transfer delays appropriate treatment for rural severe sepsis and septic shock patients: A retrospective cohort study. Crit Care Med 2015 Dec; 43(12): 2589-96.
  29. Wong T, Schlichting AB, Stoltze AJ, Fuller BM, Peacock A, Harland KK, Ahmed A, Mohr N. No decrease in early ventilator-associated pneumonia after early use of chlorhexidine. Amer J Crit Care 2016 Mar; 25(2):173-7.
  30. Fuller BM, Ferguson I, Mohr NM, Stephens RJ, Briscoe CC, Kolomiets AA, Hotchkiss RS, Kollef MH. Lung-protective ventilation initiated in the emergency department (LOV-ED): a study protocol for a quasi-experimental, before-after trial aimed at reducing pulmonary complication. BMJ Open 2016;6:e010991.
  31. Mohr NM, Harland KK, Shane DM, Ahmed A, Fuller BM, Torner JC. Inter-hospital transfer is associated with increased mortality and costs in severe sepsis and septic shock: an instrumental variables approach. J Crit Care. 2016 Jul 26; 36:187-194.
  32. Mohr NM, Harland KK, Shane DM, Ahmed A, Fuller BM, Ward M, Torner JC. Rural patients with severe sepsis or septic shock who bypass rural hospitals have increased mortality: an instrumental variables approach. Crit Care Med 2017 Jan; 45(1):85-93.
  33. Ablordeppey E, Drewry AM, Beyer A, Theodoro D, Fuller BM, Carpenter C. Diagnostic accuracy of central venous catheter confirmation by bedside ultrasound versus chest radiography in critically ill patients: A systematic review and meta-analysis. Crit Care Med  2017 Apr; 45(4): 715-724.
  34. Fuller BM, Ferguson IT, Mohr NM, Drewry AM, Palmer C, Wessman BT, Ablordeppey E, Keeperman J, Stephens RJ, Briscoe CC, Kolomiets AA, Hotchkiss RS, Kollef MH. A quasi-experimental, before-after trial examining the impact of an emergency department mechanical ventilator protocol on clinical outcomes and lung-protective ventilation in acute respiratory distress syndrome. Crit Care Med 2017 Apr; 45(4): 645-652.
    1. Also highlighted in the New England Journal of Medicine Journal Watch: http://www.jwatch.org/na43522/2017/03/03/lung-protective-strategy-acute-respiratory-distress
  35. Drewry AM, Ablordeppey E, Murray E, Stoll C, Izadi S, Dalton C, Fuller BM, Colditz G. Antipyretic Therapy in Critically Ill Septic Patients: A Systematic Review and Meta-Analysis. Crit Care Med 2017 May; 45(5): 806-813.
  36. Fuller BM, Ferguson IT, Mohr NM, Drewry AM, Palmer C, Wessman BT, Ablordeppey E, Keeperman J, Stephens RJ, Briscoe CC, Kolomiets AA, Hotchkiss RS, Kollef MH. Lung-protective ventilation initiated in the emergency department (LOV-ED): a quasi-experimental, before-after trial. Annals of Emerg Med 2017 Sept; 70(3): 406-418.
    1. Accompanied by Editorial.
    2. Also highlighted in the New England Journal of Medicine Journal Watch:  http://www.jwatch.org/na43660/2017/03/14/another-look-lung-protective-ventilation-initiated-ed
  37. Beyer A, Rees R, Wessman BT, Palmer C, Fuller BM. Blood product transfusion in emergency department patients: a case-control study of practice patterns and impact on outcome. Int J Emerg Med 2017 Dec; 10(1):5.
  38. Stephens RJ, Dettmer M, Roberts BW, Fowler S, Fuller BM. Practice patterns and outcomes associated with early sedation depth in mechanically ventilated patients: a systematic review protocol. BMJ Open 2017;7:e016437.
  39. Fuller BM, Mohr NM, Drewry AM, Ferguson IT, Trzeciak S, Kollef MH, Roberts BW. Partial pressure of arterial carbon dioxide and survival to hospital discharge among patients requiring acute mechanical ventilation: a cohort study. J Crit Care 2017; 41: 29-35.
  40. Stephens RJ, Wessman BT, Palmer C, Mohr NM, Ablordeppey E, Drewry AM, Roberts BW, Liang SY, Kollef MH, Fuller BM. Analgosedation practices and the impact of sedation depth among patients requiring mechanical ventilation in the emergency department: a cohort study. CHEST 2017 Nov; 152(5): 963-971.
    1. Also highlighted in the New England Journal of Medicine Journal Watch: https://www.jwatch.org/na44574/2017/07/19/could-greater-depth-ed-sedation-be-associated-with-worse
  41. Mohr NM, Vakkalanka JP, Faine BA, Skow B, Harland KK, Dick-Perez R, Fuller BM, Ahmed A, Simpson SQ. Serum anion gap predicts lactate poorly, but may be used to identify sepsis patients at risk for death: a cohort study. J Crit Care 2018 Apr;44: 223-228.
  42. Fuller BM, Page DB, Stephens RJ, Roberts BW, Drewry AM, Ablordeppey E, Mohr NM, Kollef MH. Pulmonary mechanics and mortality in mechanically ventilated patients without acute respiratory distress syndrome: a cohort study. Shock. 2018 Mar; 49(3): 311-316.
  43. Stephens RJ, Dettmer MR, Roberts BW, Ablordeppey E, Fowler SA, Kollef MH, Fuller BM. Practice patterns and outcomes associated with early sedation depth in mechanically ventilated patients: a systematic review and meta-analysis. Crit Care Med. March 2018- 46(3): 471-479.
    1. Accompanied by Editorial.
    2. Featured in Annals of Emergency Medicine Systematic Review Snapshot Series.
  44. Roberts BW, Mohr NM, Ablordeppey E, Drewry AM, Ferguson IT, Trzeciak S, Kollef MH, Fuller BM. Association between arterial pressure of arterial carbon dioxide and survival to hospital discharge among patients diagnosed with sepsis in the emergency department. Crit Care Med. March 2018- 46(3): e213-e220.
  45. Page D, Mohr NM, Ablordeppey E, Trzeciak S, Kollef MH, Roberts BW, Fuller BM. Emergency department hyperoxia is associated with increased mortality in mechanically ventilated patients: a cohort study. Crit Care. 2018 Jan 18;22(1):9.
    1. Accompanied by Editorial.
  46. Page D, Drewry AM, Ablordeppey E, Mohr NM, Kollef MH, Fuller BM. Thirty-day hospital readmissions among mechanically ventilated emergency department patients. Emerg Med J. 2018 Apr; 35(4): 252-256.
  47. Si S, Yan Y, Fuller BM, Liang SY. Predicting complicated outcomes in spinal cord injury patients with urinary tract infection: development and internal validation of a risk model. J Spinal Cord Med. 2018 Feb 21: 1-8.
  48. Drewry AM, Ablordeppey E, Murray ET, Fuller BM, Kollef MH, Hotchkiss RS. Monocyte function and clinical outcomes in febrile and afebrile patients with severe sepsis. Shock. 2018 Oct; 50(4): 381-387.
  49. Clyde T, Coletta M, Jones C, Kilgannon JH, Fuller BM, Trzeciak S, Roberts BW. Effects of hypercapnia in sepsis: protocol for a systematic review of clinical and preclinical data. Systematic Reviews. 2018 Oct 22; 7(1): 171.
  50. Fuller BM, Mohr NM, Roberts BW, Carpenter CR, Kollef MH, Avidan MS. Protocol for a multicenter, prospective cohort study of practice patterns and clinical outcomes associated with Emergency Department SEDation for mechanically ventilated patients: The ED-SED Study. BMJ Open. 2018;8:e023423.doi:10.1136/bmjopen-2018-023423.
  51. Mohr NM, Harland KK, Shane DM, Dick-Perez R, Miller D, Miyake C, Kannedy L, Fuller BM, Ahmed A, Torner JC. Emergency department charges predict severity of illness and mortality in patients with severe sepsis and septic shock: A cohort study. BMC Emergency Medicine. 2018 Dec 29;18(1):62.
  52. Ablordeppey E, Drewry AM, Theodoro DL, Tian L, Fuller BM, Griffey RT. Current practices in central venous catheter position confirmation by point of care ultrasound: a survey of early adopters. SHOCK. 2019 May; 51(5): 613-618.
  53. Roberts BW, Kilgannon JH, Hunter BR, Puskarich MA, Pierce L, Donnino M, Leary M, Jones C, Fuller BM, Kline JA, Jones AE, Shapiro NI, Abella BS, Trzeciak S. Association between elevated mean arterial blood pressure and neurological outcome after resuscitation from cardiac arrest. Crit Care Med. 2019 Jan;47(1):93-100.
  54. Burnham JP, Wallace MA, Fuller BM, Shupe A, Burnham CAD, Kollef MH. Clinical impact of expedited pathogen identification and susceptibility testing for gram-negative bacteremia and candidemia using the accelerate PhenoTM system. J Applied Lab Med. 2019 Jan; 3(4): 569-579.
  55. Kilgannon JH, Hunter BR, Puskarich MA, Shea L, Fuller BM, Jones C, Donnino M, Kline JA, Jones AE, Shapiro NI, Abella BS, Trzeciak S, Roberts BW. Partial pressure of arterial carbon dioxide after resuscitation from cardiac arrest and neurological outcome: a prospective multi-center protocol-directed cohort study. Resuscitation. 2019 Feb; 135: 212-220.
  56. Stephens RJ, Siegler J, Fuller BM. Mechanical ventilation in the pre-hospital and emergency department environment. Respir Care 2019; 64(5): 595-603.
  57. Evans EM, Doctor RJ, Gage BF, Hotchkiss RS, Fuller BM, Drewry AM. The association of fever and antipyretic medication with outcomes in mechanically ventilated patients: a cohort study. SHOCK. 2019 August; 52(2): 152-159.
  58. Fuller BM, Roberts BW, Mohr NM, Knight WA, Adeoye O, Pappal RD, Marshall S, Alunday R, Dettmer M, Goyal M, Gibson C, Levine BJ, Gardner-Gray JM, Mosier J, Dargin J, Mackay F, Johnson NJ, Lokhandwala S, Hough CL, Tonna JE, Tsolinas R, Lin F, Qasim ZA, Harvey CE, Bassin B, Stephens RJ, Yan Y, Carpenter CR, Kollef MH, Avidan MS. The ED-SED Study: a multicenter, prospective cohort study of practice patterns and clinical outcomes associated with Emergency Department SEDation for mechanically ventilated patients. Crit Care Med. 2019 Nov; 47(11): 1539-1548.
    1. Featured in SCCM’s webcast series, “Journal Club: Critical Care Medicine”.
    2. Also highlighted in the New England Journal of Medicine Journal Watch: https://www.jwatch.org/na49728/2019/08/21/level-sedation-mechanically-ventilated-ed-patients
    3. Voted as the 2nd most impactful manuscript in 2019 by the ACEP CCM Section
  59. Sabapathi P, Roberts MB, Fuller BM, Puskarich MA, Jones CW, Kilgannon HJ, Braz V, Creel-Bulos C, Scott N, Tester KL, Mazzarelli A, Trzeciak S, Roberts BW. Validation of a 5-item tool to measure patient assessment of clinician compassion in the emergency department. BMC Emerg Med. 2019 Nov 4; 19(1):63.
  60. Pappal RD, Roberts BW, Mohr NM, Ablordeppey EA, Wessman BT, Drewry AM, Yan Y, Kollef MH, Avidan MS, Fuller BM. Protocol for a prospective, observational cohort study of awareness in mechanically ventilated patients admitted from the emergency department: The ED-AWARENESS Study. BMJ Open. 2019;9:e033379. doi: 10.1136/bmjopen-2019-033379.
  61. Manasco AT, Stephens RJ, Yaeger LH, Roberts BW, Fuller BM. Ketamine sedation in mechanically ventilated patients: a systematic review and meta-analysis. J Crit Care. 2019 Dec 9; 56: 80-88.
  62. George BP, Vakkalanka JP, Harland KK, Faine B, Rewitzer S, Zepeski A, Fuller BM, Mohr NM, Ahmed A. Sedation depth is associated with increased hospital length of stay in mechanically ventilated air transport patients: a cohort study. Prehosp Emerg Care. 2019 Dec 17: 1-18
  63. Pappal RD, Roberts BW, Winkler W, Yaeger LH, Stephens RJ, Fuller BM. Awareness and bispectral index (BIS) monitoring in mechanically ventilated patients in the emergency department and intensive care unit: a systematic review protocol. BMJ Open. 2020 Mar 4;10(3):e034673.
  64. Wessman BT, Page D, Greer M, Fuller BM. Emergency Medicine/Critical Care Medicine (EM/CCM) Trainees’ Performance on Standardized Critical Care Medicine Exams: A Ten-Year Review. J Emerg Med. 2020 April 1.  pii: S0736-4679(20)30113-X. doi: 10.1016/j.jemermed.2020.02.017.
  65. Foley TM, Philpot B, Davis A, Swanson MB, Harland KK, Kuhn J, Fuller BM, Mohr NM. Implementation of an ED-based bundled mechanical ventilation protocol improves adherence to lung-protective ventilation. Am J Emerg Med. 2020 [accepted for publication]
  66. Ablordeppey EA, Oberle AM, Drewry AM, Wessman BT, Anderson AL, Isakow WX, Theodoro DL, Fuller BM, Boyle WA. Focused POCUS: a concise point-of-care ultrasound training program for critical care providers. [submitted for publication]
  67. Mohr NM, Skow B, Bell A, McDanel J, Fuller BM, Simpson S, Ward M. Improving access to high quality sepsis care: sepsis utilization in a South Dakota emergency telemedicine network. [submitted for publication]
  68. Clyde TP, Coletta M, Jones C, Kilgannon H, Fuller BM, Trzeciak S, Roberts BW. Effects of hypercapnia in sepsis: a systematic review of clinical and preclinical data [submitted for publication]
  69. Ablordeppey EA, Drewry AM, Anderson A, Casali D, Wallace L, Kane D, House S, Fuller BM, Griffey R, Theodoro DL. Bedside ultrasound-guided central venous catheter confirmation in critically ill patients [submitted for publication]
  70. Silver P, Kremer P, Fuller BM, Reed-Watts P, Kollef MH. A prospective trial of high flow oxygen versus low flow oxygen in patients undergoing tracheostomy for respiratory failure [submitted for publication]