Current Studies

Opeolu Adeoye, MD, MS

  • A randomized, double blind, multicenter, multinational, placebo controlled, parallel group, single dose, adaptive efficacy and safety study of Glenzocimab used as an add-on therapy on top of standard of care in the 4.5 hours following an acute ischemic stroke (ACTISAVE)
  • Acute Stroke Biobank

Kevin Baumgartner, MD

  • The use of Dexmedetomidine in the Emergency Department: a prospective observational cohort study (DEX in the ED)
  • Evaluation of patients envenomated by native North American crotalids for antibodies directed against snake venom

Patricia Cavazos-Rehg, MD

  • A mHealth tool to support recovery among adults with substance use disorder (uMat-R)

Dennis Dietzen, MD

  • Detection of protein targets in dermal interstitial fluid (Abbott ISF)

Stephanie Fritz, MD, MSCI

  • Short and Long Term Outcomes of Doxycycline versus Trimethoprim-Sulfamethoxazole for Skin and Soft Tissue Infection Treatment

Derek Holder, MD

  • A phase III, prospective, double-blind, randomized, placebo-controlled trial of Thrombolysis in IMaging-Eligible, Late-window patients to assess the Efficacy and Safety of tenecteplaSe (TIMELESS)

Stacey House, MD, PhD

  • Acute Respiratory infections Global Outpatient Study (ARGOS)
  • A randomized, double-blind, placebo controlled dose-ranging study of Auxora in patients with acute pancreatitis and accompanying systemic inflammatory response syndrome (CARPO)
  • Clinical evaluation of the Xpert Xpress CT/NG test in male urine and extragenital specimens (Cepheid 248C1)
  • Clinical evaluation of the Xpert Xpress CT/NG test in female urogenital specimens (Cepheid 248C2)
  • Clinical evaluation of the Xpert Xpress CT/NG test in female extragenital specimens (Cepheid 248C3)
  • Follow-up of mTBI patients discharged using a BrainScope based clinical decision rule (MEDO BrainScope)
  • ThRombosis exclUsion STudy for STA® – Liatest® D-Di XL (TRUST)
  • US Platform to measure effectiveness of seasonal influenza, COVID-19, and other respiratory virus vaccines for the prevention of acute illness in ambulatory settings (US Flu VE)
  • Written exposure therapy to Improve lives after Stress Exposure (WISE)
  • Clinical Evaluation of the i-STAT hs-TnI Test to Aid in the Diagnosis of Myocardial Infarction (MI) (Abbott Troponin)
  • Clinical Evaluation of the Xpert® GI Panel using Stool and Rectal Swab Specimens (Cepheid GI 262C2)
  • cobas® CT/NG/MG Nucleic acid test for use on the cobas® Liat® System: Clinical Performance Evaluation (Roche STI)
  • Clinical Evaluation of the BinaxNOW™ COVID-19 Ag / Flu A & B Combo Card (Binax COVID Flu)
  • Randomized Controlled Trial of Vitamin D to reduce racial disparity in chronic pain following Motor Vehicle Collision: The VENTURE Trial (Vitamin D to ENhance TraUma REcovery) (Venture)
  • Specimen Collection for the Evaluation of Alere NT-proBNP for Alinity i System in an Emergency Department Setting for Heart Failure (LANER-HF) (Abbott proBNP)

Jin-Moo Lee, MD

  • The Washington University School of Medicine and BJC Healthcare Electronic Biobank for Clinical Neuroscience (NeuroBank)

Stephen Liang, MD

  • Efficacy of SynEx™ wound rinse in civilian surrogates of combat injury wounds (SynEx)

Phillip Mudd, MD, PhD

  • Prospective Bronchoscopy Sample Collection from Patients with Acute Influenza Diagnosed in the Emergency Department

Peter Panagos, MD

  • Multi-arm Optimization of Stroke Thrombolysis: a single blinded, randomized controlled adaptive, multi-arm, adjunctive-thrombolysis efficacy trial in ischemic stroke (MOST)
  • rFVIIa for Acute Hemorrhagic Stroke Administered at Earliest Time (FASTEST) Trial

Robert Poirier, MD

  • A phase IIIb, multicenter, randomized, double-blind, placebo-controlled, clinical efficacy study of Baloxavir Marboxil for the reduction of direct transmission of influenza from otherwise healthy patients to household contacts (Centerstone)

Wilson Ray, MD

  • A phase 2a, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of MT-3921 in subjects with acute traumatic cervical spinal cord injury (MT-3921-A01)
  • A randomized, double-blinded, placebo-controlled proof of concept study to assess the safety and efficacy of Elezanumab in acute traumatic cervical spinal cord injury (AbbVie)

Pratik Sinha, MD

  • The PREcision-based Critical Care In Sepsis study (PRECCISE)