Tiffany M Osborn, MD, MPH, FACEP
Professor, Surgery & Emergency Medicine
- Phone: 314-362-4114
Tiffany Osborn, MD, MPH, currently serves on the Centers for Disease Control and Prevention’s National Sepsis Task Force. She additionally serves on the National Quality Measures Technical Expert Panel for the ACEP’s Clinical Emergency Data Registry. She is a representative to the Surviving Sepsis Campaign, is on the resuscitation guidelines writing committee and an author of the international guidelines on severe sepsis and septic shock management. She worked on the National Quality Forum’s Infectious Disease Committee, which vets potential CMS measures for possible national implementation. Dr. Osborn is a sepsis consultant for the Institute of Healthcare Improvement and assisted them in implementing sepsis measures across multiple hospitals in New York. She currently serves as the BJH physician hospital champion overseeing the implementation of CMS compliant sepsis quality measures. She has several publications in sepsis, resuscitation and critical care training. Dr. Osborn completed her emergency medicine residency at the University of Maryland and her surgical/trauma critical care fellowship at the R Adams Cowley Shock Trauma Center in Baltimore, MD. Her Masters of Public Health was completed at the London School of Hygiene and Tropical Medicine before being recruited as a trial clinician by the Intensive Care Nationsal Audit and Research Centre (ICNARC) in London, England. She worked at ICNARC as the trial clinician for Protocolised Management in Sepsis (ProMISe) – a government funded RCT across 56 sites in England. Upon her return to the US, she was awarded a scholarship to the Olin Business School’s Leadership for Women and currently is an Associate Professor with joint appointments in the Department of Surgery and the Department of Emergency Medicine. She works in the Surgical / Trauma Intensive Care Unit and Emergency Department at Washington University School of Medicine in St. Louis, MO.
- B.S., Biology, Minor: Chemistry, University of Houston, Houston, TX, 1992
- Medical School: University of Texas Health Sciences Center, San Antonio TX 1997
- Masters Degree: (Public Health Research), London School of Hygiene and Tropical Medicine, London, England 2009
- Residency: Emergency Medicine, University of Maryland Medical System, Baltimore, MD 2000
- Fellowship: Trauma and Surgical Critical Care, R Adams Cowley Shock Trauma Center, Baltimore, MD, 2002
- MPH (Research Track), London School of Hygiene and Tropical Medicine, London, England, 2009
Licensure and Board Certification
- Critical Care ( European Society of Intensive Care Medicine)
- Emergency Medicine
Honors and Awards
- Outstanding Community Service Award, University of Texas Health Science Center Medical Dean’s Award, University of Texas, San Antonio, TX, 1997
- Dedication Award, Emergency Medicine Residents’ Association, 2000
- Resident of the Year, Maryland College of Emergency Physicians, 2000
- Award: “Epidemiology of Sepsis in Trauma”, Society of Critical Care Medicine Innovative Research, 2002
- Fellowship in American College of Emergency Physicians (ACEP), 2006
- Respiratory Therapy Annual Award, Barnes Jewish Hospital, St. Louis, MO, 2012
- Scholarship Award: Executive Leadership Program for Women (US News and World Report rank #1 globally), Olin Business School, St. Louis, MO
- Hospital Physician Champion, Sepsis Quality Initiative, Barnes Jewish Hospital, St. Louis, MO, 2014
- Fellowship in the American College of Critical Care Medicine (contingent upon FCCM induction Feb 2016), 2015
Peer reviewed manuscripts
- Mouncey PR, Osborn TM, Power GS, Harrison DA, Sadique MZ, Grieve RD, Jahan R, Harvey SE, Bell D, Bion JF, Coats TJ, Singer M, Young JD, Rowan KM; ProMISe Trial Investigators. Trial of Early, Goal-Directed Resuscitation for Septic Shock. N Engl J Med. 2015 Apr 2;372(14):1301-11.
- Casserly B, Phillips GS, Schorr C, Dellinger RP, Townsend SR, Osborn TM, Reinhart K, Selvakumar N, Levy MM. Lactate Measurements in Sepsis-Induced Tissue Hypoperfusion: Results From the Surviving Sepsis Campaign Database. Crit Care Med. 2015 Mar;43(3):567-73.
- Levy MM, Rhodes A, Phillips GS, Townsend SR, Schorr CA, Beale R, Osborn T, Lemeshow S, Chiche JD, Artigas A, Dellinger RP. Surviving Sepsis Campaign: Association Between Performance Metrics and Outcomes in a 7.5-Year Study. Crit Care Med. 2015 Jan;43(1):3-12.
- Levy MM, Rhodes A, Phillips GS, Townsend SR, Schorr CA, Beale R, Osborn T, Lemeshow S, Chiche JD, Artigas A, Dellinger RP. Surviving Sepsis Campaign: Association Between Performance Metrics and Outcomes in a 7.5-Year Study. Intensive Care Med. 2014 Nov;40(11):1623-33.
- Osborn TM, Phillips G, Lemeshow S, Townsend S, Schorr CA, Levy MM, Dellinger RP. Sepsis severity score: an internationally derived scoring system from the surviving sepsis campaign database*. Crit Care Med. 2014 Sep;42(9):1969-76.
- Ginde AA, Blatchford PJ, Trzeciak S, Hollander JE, Birkhahn R, Otero R, Osborn TM, Moretti E, Nguyen HB, Gunnerson KJ, Milzman D, Gaieski DF, Goyal M, Cairns CB, Rivers EP, Shapiro NI. Age-related differences in biomarkers of acute inflammation during hospitalization for sepsis. Shock 2014 Aug;42(2):99-107.
- Ferrer R, Martin-Loeches I, Phillips G, Osborn T, Townssend S, Dellinger RP, Artigas A, Schorr C, Levy MM. Empiric Antibiotic Treatment Reduces Mortality in Severe Sepsis and Septic Shock From the First Hour: Results From a Guideline-Based Performance Improvement Program. Crit Care Med 2014 Aug;42(8):1749-55.
- Power GS, Harrison DA, Mouncey PR, Osborn TM, Harvey SE, Rowan KM. The Protocolised Management in Sepsis (ProMISe) trial statistical analysis plan. Crit Care Resusc. 2013 Dec;15(4):311-7.
- Osborn TM, Levy M, Dellinger RP, Annane D. The Surviving Sepsis Campaign Author Reply. Crit Care Med. 2013 Oct;41(10):e293-4.
- ProCESS/ARISE/ProMISe Methodology Writing Committee, Huang DT, Angus DC, Barnato A, Gunn SR, Kellum JA, Stapleton DK, Weissfeld LA, Yealy DM, Peake SL, Delaney A, Bellomo R, Cameron P, Higgins A, Holdgate A, Howe B, Webb SA, Williams P, Osborn TM, Mouncey PR, Harrison DA, Harvey SE, Rowan KM. Harmonizing international trials of early goal-directed resuscitation for severe sepsis and septic shock: methodology of ProCESS, ARISE and ProMISe. Intensive Care Medicine. 2013. Oct;39(10):1760-75. Epup 2013 Aug 30.
- Perman SM, Chang AM, Hollander JE, Gaieski DF, Trzeciak S, Birkhahn R, Otero R, Osborn TM, Moretti E, Nguyen HB, Gunnerson KJ, Milzman D, Goyal M, Cairns CB, Ngo L, Rivers EP, Shapiro NI. Relationship between B-type natriuretic peptide and adverse outcome in patients with clinical evidence of sepsis presenting to the emergency department. Academic Emerg Med 2011 Feb;18(2):219-22. doi:10.1111/j.1553-2712.2010.00968.x. Epub 2011 Jan 28.PMID: 21314784
- Casserly B, Gerlach H, Phillips GS, Gemeshow S, Marshall JC, Osborn TM, Levy MM. Low dose steroids in adult septic shock: Results of the Surviving Sepsis Campaign. Intensive Care Med. 2012 Dec;38(12):1946-54. Doi: 10.1007/s00134-012-2720-z. Epub 2012 Oct 12.
- Levy MM, Artigas A, Phillips GS, Rhodes A, Beale R, Osborn T, Vincent JL, Townsend S, Lemeshow S, Dellinger RP. Outcomes of the Surviving Sepsis Campaign in intensive care units in the USA and Europe: a prospective cohort study. Lancet Infect Dis. 2012 Dec;12(12):919-24. doi:10.1016/S1473-3099(12)70239-6
- Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb SA, Beale RJ, Vincent JL, Moreno R; and the Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup. Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock 2012. Critical Care Med 2013 Feb;41(2):580-637.
Invited Publications (E.g. reviews, book chapters, etc)
- Ebarb J, Sculley K, Nguyen HB, Sawyer RG, Barlotta K, Osborn TM. Lactate as a prognostic indicator in sepsis syndrome. Inten Care Med. 2005 Sep;31(Suppl 1)S48.
- Deblieux P, Osborn TM (eds.). Critical Care in Emergency Medicine. Emergency Medicine Clinics of North America. August 2008:26(3).
- Osborn TM, Alagappan K, Emlet L, et al. The Patient Care Continuum. From the Emergency Department to the Intensive Care Unit. 25 Years of Progress and Innovation in Intensive Care Medicine. 2008. European Society of Intensive Care Medicine, pp. 189-197
- Rivers EP, Nguyen HB, Osborn TM, et al. Early Goal-Directed Therapy in Severe Sepsis and Septic Shock. 25 Years of Progress and Innovation in Intensive Care Medicine. 2008. European Society of Intensive Care Medicine, pp. 383-391.
- Osborn TM, Farcy D. Review of the Updated Surviving Sepsis Campaign. American Academy of Emergency Medicine. Podcast audio. May 2013. http://www.aaem.org/publications/podcasts/critical-care-in-emergency-medicine
- Osborn TM. Update on Sepsis Management Guidelines. American Academy of Emergency Physicians. Podcast audio. January 2014.
- Osborn TM. Septic shock: Acute management of the Morbidly Obese Patient. Society of Critical Care Medicine. Podcast audio. March 2014. http://www.survivingsepsis.org/Resources/Pages/Media.aspx
- Osborn TM. Doctor: Now is the time to get your flu shot [Video File]. Gennet Satellite Information Network. KSDK St. Louis, Channel 5. 21 Sept. 2014. Retrieved from http://www.ksdk.com/story/news/health/2014/09/21/doctor-now-is-the-time-to-get-your-flu-shot/16000079/
- Osborn TM. SGEM#113:EGDT-ProMISe(s) ProMISe(s). The Skeptics’ Guide to Emergency Medicine. Podcast audio. March 29, 2015. http://thesgem.com/2015/03/sgem113-egdt-promises-promises/
- Farcy D, Chiu W, Marshall J, Osborn T (eds.). Critical Care: Emergency Medicine, Second Edition. New York: McGraw Hill. 2015.